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Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary
Science | AAAS
The female ovary contains a finite number of oocytes, and their release at ovulation becomes sporadic and disordered with aging and with obesity,...
27 miesięcy temu
‘Nursing must take a united position on clinical supervision’
Nursing Times
The Royal College of Nursing's professional lead for mental health Stephen Jones on how it is imperative that nurses take a united position...
30 miesięcy temu
TpiA is a Key Metabolic Enzyme That Affects Virulence and Resistance to Aminoglycoside Antibiotics through CrcZ in Pseudomonas aeruginosa
ASM Journals
Carbon metabolism plays an essential role in bacterial pathogenesis and susceptibility to antibiotics. In Pseudomonas aeruginosa, Crc, Hfq, and a small RNA,...
36 miesięcy temu
Resistance evolution can disrupt antibiotic exposure protection through competitive exclusion of the protective species
Nature
Antibiotic degrading bacteria can reduce the efficacy of drug treatments by providing antibiotic exposure protection to pathogens.
27 miesięcy temu
Inter-species interactions alter antibiotic efficacy in bacterial communities
Nature
We demonstrate that multi-drug resistant Stenotrophomonas maltophilia can provide high levels of antibiotic protection to otherwise sensitive P. aeruginosa.
36 miesięcy temu
Follicular metabolic alterations are associated with obesity in mares and can be mitigated by dietary supplementation
Nature
We hypothesized that obesity in the mare promotes follicular lipid accumulation and altered mitochondrial function of oocytes and granulosa cells.
7 miesięcy temu
Depletion of oocyte dynamin-related protein 1 shows maternal-effect abnormalities in embryonic development
Science | AAAS
We find that Drp1-deleted oocytes undergo fertilization and preimplantation development but that peri- and postimplantation embryonic lethality is markedly...
28 miesięcy temu
Tobacco
Alcohol and Drug Foundation
Tobacco is a plant with stimulant effects. Nicotine is one of the many naturally occurring chemicals found in tobacco, and speeds up the messages travelling...
92 miesiące temu
Optimised chronic infection models demonstrate that siderophore ‘cheating’ in Pseudomonas aeruginosa is context specific
Nature
The potential for siderophore mutants of Pseudomonas aeruginosa to attenuate virulence during infection, and the possibility of exploiting...
87 miesięcy temu
FosA3 emerging in clinical carbapenemase-producing C. freundii
Frontiers
Fosfomycin (FOS) is an effective antibiotic against multidrug-resistant Enterobacterales, but its effectiveness is reducing.
3 miesiące temu