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Myc Antibody (C-33): sc-42
- Myc Antibody (C-33) is a mouse monoclonal IgG1 κ, cited in 335 publications, provided at 200 µg/ml
- raised against full length c-Myc of human origin
- Anti-Myc Antibody (C-33) is recommended for detection of c-Myc p67 and c-Myc tagged fusion proteins of mouse, rat, human and avian origin by WB, IP, IF and ELISA
- Anti-Myc Antibody (C-33) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for Gel Supershift and ChIP applications (sc-42 X, 200 µg/0.1 ml)
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Myc (C-33): sc-42.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Myc Antibody (C-33) for WB applications. These reagents are now offered in bundles with Myc Antibody (C-33) (see ordering information below).
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c-Myc Antibody (C-33) is an IgG1 κ mouse monoclonal c-Myc antibody (also designated c-Myc antibody or Myc antibody) that detects c-Myc p67 and c-Myc tagged fusion proteins of mouse, rat and human origin by WB, IP, IF and ELISA. c-Myc Antibody (C-33) is available as the non-conjugated anti-c-Myc antibody form, as well as multiple conjugated forms of anti-c-Myc antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas. The presence of three sequence motifs in the c-Myc COOH terminus, including the leucine zipper, the helix-loop-helix and a basic region, provided initial evidence for a sequence-specific binding function. A basic region helix-loop-helix leucine zipper motif (bHLH-Zip) protein, designated Max, specifically associates with c-Myc, N-Myc and L-Myc proteins. The Myc-Max complex binds to DNA in a sequence-specific manner under conditions where neither Max nor Myc exhibits appreciable binding. Max can also form heterodimers with at least two additional bHLH-Zip proteins, Mad 1 and Mxi1, and Mad 1-Max dimers have been shown to repress transcription through interaction with mSin3.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Myc Antibody (C-33) | sc-42 | 200 µg/ml | $310.00 | |||
Myc Antibody (C-33): m-IgG Fc BP-HRP Bundle | sc-528091 | 200 µg Ab; 10 µg BP | $348.00 | |||
Myc Antibody (C-33): m-IgGκ BP-HRP Bundle | sc-520389 | 200 µg Ab, 40 µg BP | $348.00 | |||
Myc Antibody (C-33): m-IgG1 BP-HRP Bundle | sc-542755 | 200 µg Ab; 20 µg BP | $348.00 | |||
Myc Antibody (C-33) X | sc-42 X | 200 µg/0.1 ml | $310.00 | |||
Myc Antibody (C-33) AC | sc-42 AC | 500 µg/ml, 25% agarose | $408.00 | |||
Myc Antibody (C-33) HRP | sc-42 HRP | 200 µg/ml | $310.00 | |||
Myc Antibody (C-33) FITC | sc-42 FITC | 200 µg/ml | $324.00 | |||
Myc Antibody (C-33) PE | sc-42 PE | 200 µg/ml | $337.00 | |||
Myc Antibody (C-33) Alexa Fluor® 488 | sc-42 AF488 | 200 µg/ml | $350.00 | |||
Myc Antibody (C-33) Alexa Fluor® 546 | sc-42 AF546 | 200 µg/ml | $350.00 | |||
Myc Antibody (C-33) Alexa Fluor® 594 | sc-42 AF594 | 200 µg/ml | $350.00 | |||
Myc Antibody (C-33) Alexa Fluor® 647 | sc-42 AF647 | 200 µg/ml | $350.00 | |||
Myc Antibody (C-33) Alexa Fluor® 680 | sc-42 AF680 | 200 µg/ml | $350.00 | |||
Myc Antibody (C-33) Alexa Fluor® 790 | sc-42 AF790 | 200 µg/ml | $350.00 |