Tretinoin, tailored to you.

Custom Rx Treatment is a customized skincare treatment intended to be used on the face. It’s a compounded drug product, which means it’s a mixture of different ingredients selected based on your specific needs. While compounded medications are not FDA-approved, they serve an important patient need—especially when FDA-approved medication is not available for treatment.

Our team of experts, including dermatologists and our very own Chief Medical Officer, created the Custom Rx Treatment formulations and Enriching Cream, a 24-hour moisturizer, to pair with it.

If prescribed, several different ingredients may end up in your formulation of Custom Rx Treatment. Through Ro, you’ll be connected with a US-licensed healthcare professional who will select the most appropriate combination of ingredients, tailoring the formulation to your specific skin concerns and goals. You’ll receive information about the ingredients in your formulation in your treatment plan.

Custom Rx Treatment is made with a blend of ingredients that were hand-selected by a dermatologist and customized to fit your needs. Depending on your specific skin type, concerns, and goals, the ingredients in your Custom Rx Treatment may include:

• Tretinoin (see Important Safety Information)

• Azelaic acid (see Important Safety Information)

• Niacinamide

• Vitamin E acetate

• Tranexamic acid

• Ceramides

• Hyaluronic acid

If prescribed, you will receive a detailed treatment plan that describes which ingredients are included in your custom formulation.

Custom Rx Treatment is tailored to target a wide range of skin concerns. These include:

• Dark spots

• Fine lines and wrinkles

• Acne

• Clogged pores

• Discoloration

• Uneven skin tone

• Skin firmness

• Skin texture

• Inflammation

• Redness

• Dryness

• Dullness

During your online visit, you will be asked about your specific skin goals, including which concerns you’d most like to address. If prescribed, your bottle of Custom Rx Treatment will include ingredients that are selected based on the concerns and goals you’ve indicated.

When using Custom Rx Treatment, the timing of the effects of your treatment will be dependent on many factors, including your specific skincare goals (e.g., reducing the appearance of fine lines and wrinkles, reducing redness, etc.), how severe your symptoms are, how well you tolerate the treatment, and others. It is also important to understand that—for certain treatments—your skin may appear worse before it gets better. Depending on the treatment you are prescribed, you will receive detailed information on the formulation, what to expect and when, as well as tips on how to mitigate any side effects such as redness, peeling, and flaking that may occur as your skin acclimates to the treatment.

In many cases, yes. Depending on your specific treatment, your provider may recommend avoiding skincare products with ingredients such as salicylic acid, glycolic acid, or benzoyl peroxide—at least during the beginning weeks of treatment. If you have any questions about specific products, you can message your provider for guidance. If you’re using other topical prescription medications, make sure to tell your provider.

Prescription skincare can make your skin more prone to irritation and sensitivity to the sun. To help with dryness, Ro offers Enriching Cream, a rich yet non-greasy moisturizer that enhances your Custom Rx Treatment routine. It’s tested to deliver instant and 24-hour hydration, helps support the skin barrier, and reduces the look of both dryness and flakiness for skin that feels softer and smoother.

Of course we recommend using broad-spectrum sunscreen with an SPF of at least 30 every day.