EP1073420A4 - Specially devised neuronal implants for reconstruction of damaged central nervous system - Google Patents

Specially devised neuronal implants for reconstruction of damaged central nervous system

Info

Publication number
EP1073420A4
EP1073420A4 EP99919517A EP99919517A EP1073420A4 EP 1073420 A4 EP1073420 A4 EP 1073420A4 EP 99919517 A EP99919517 A EP 99919517A EP 99919517 A EP99919517 A EP 99919517A EP 1073420 A4 EP1073420 A4 EP 1073420A4
Authority
EP
European Patent Office
Prior art keywords
reconstruction
nervous system
central nervous
specially devised
damaged central
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99919517A
Other languages
German (de)
French (fr)
Other versions
EP1073420A2 (en
Inventor
Abraham Shahar
Zvi Nevo
Semion Rochkind
Steven A Goldman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1073420A2 publication Critical patent/EP1073420A2/en
Publication of EP1073420A4 publication Critical patent/EP1073420A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/08—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system
EP99919517A 1998-05-14 1999-05-14 Specially devised neuronal implants for reconstruction of damaged central nervous system Withdrawn EP1073420A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8550298P 1998-05-14 1998-05-14
US85502P 1998-05-14
PCT/IL1999/000257 WO1999058042A2 (en) 1998-05-14 1999-05-14 Specially devised neuronal implants for reconstruction of damaged central nervous system

Publications (2)

Publication Number Publication Date
EP1073420A2 EP1073420A2 (en) 2001-02-07
EP1073420A4 true EP1073420A4 (en) 2004-09-08

Family

ID=22192041

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99919517A Withdrawn EP1073420A4 (en) 1998-05-14 1999-05-14 Specially devised neuronal implants for reconstruction of damaged central nervous system

Country Status (3)

Country Link
EP (1) EP1073420A4 (en)
AU (1) AU3728099A (en)
WO (1) WO1999058042A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002039948A2 (en) * 2000-11-14 2002-05-23 N.V.R. Labs Inc. Cross-linked hyaluronic acid-laminin gels and use thereof in cell culture and medical implants
CA2604394A1 (en) * 2005-01-19 2006-07-27 Fidia Advanced Biopolymers S.R.L. Hyaluronic acid derivative and neural stem cells for sci and pnt regeneration
CA2603443C (en) * 2005-03-31 2019-01-08 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Light as a replacement for mitogenic factors on progenitor cells
GB0512216D0 (en) 2005-06-15 2005-07-27 Capsant Neurotechnologies Ltd Device
GB0512214D0 (en) 2005-06-15 2005-07-27 Capsant Neurotechnologies Ltd Method
CN103555747B (en) * 2013-10-22 2015-04-08 深圳先进技术研究院 Gliocyte bFGF expression enhancement system, as well as construction method and application thereof
CN112094805A (en) * 2020-08-24 2020-12-18 四川大学 Preparation method of spinal cord fibroblasts

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019195A1 (en) * 1991-04-25 1992-11-12 Brown University Research Foundation Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
WO1993014790A1 (en) * 1992-01-23 1993-08-05 New York University A method for transplanting cells into the brain and therapeutic uses therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4774093A (en) * 1985-06-25 1988-09-27 Fmc Corporation Polysaccharide compositions, preparation and uses
CA2103565A1 (en) * 1991-02-18 1992-08-19 Alain O. A. Miller Support for the culture of cells and method for preparing such a support

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019195A1 (en) * 1991-04-25 1992-11-12 Brown University Research Foundation Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
WO1993014790A1 (en) * 1992-01-23 1993-08-05 New York University A method for transplanting cells into the brain and therapeutic uses therefor

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ROCHKIND S ET AL.: "A combined procedure of cultured embryonic cells implantation and low power laser treatment to cure paraplegic rats following complete spinal cord transection", CLINICAL NEUROLOGY AND NEUROSURGERY, vol. 99 suppl. 1, July 1997 (1997-07-01), pages S143, XP002286486 *
ROCHKIND S ET AL: "A combined procedure utilizing cultured embryonal cell implantation and low power laser treatment to cure paraplegic rats following complete spinal cord transection", PROCEEDINGS OF THE 11TH INTERNATIONAL CONGRESS OF NEUROLOGICAL SURGERY, AMSTERDAM, THE NETHERLANDS, 6 July 1997 (1997-07-06) - 11 July 1997 (1997-07-11), pages 1903 - 1908, XP009032880 *
ROCHKIND S ET AL: "Transplantation of embryonal spinal cord nerve cells cultured on biodegradable microcarriers followed by low power laser irradiation for the treatment of traumatic paraplegia in rats", NEUROLOGICAL RESEARCH, vol. 24, no. 4, June 2002 (2002-06-01), pages 355 - 360, XP002286758, ISSN: 0161-6412 *
See also references of WO9958042A3 *
SHAHAR A ET AL: "Tissue culture models in the study of neuroregeneration and neurodegenerative processes", JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, vol. 54, no. SUPPL., 1995, Symposium on Brain Research and Society;Barcelona, Spain; September 21-24, 1995, pages 20S - 21S, XP009032967, ISSN: 0022-3069 *

Also Published As

Publication number Publication date
WO1999058042A3 (en) 2000-04-06
AU3728099A (en) 1999-11-29
EP1073420A2 (en) 2001-02-07
WO1999058042A2 (en) 1999-11-18

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