EP1005355A4 - Method of treating gastrointestinal ulcers and compositions therefor - Google Patents

Method of treating gastrointestinal ulcers and compositions therefor

Info

Publication number
EP1005355A4
EP1005355A4 EP98919780A EP98919780A EP1005355A4 EP 1005355 A4 EP1005355 A4 EP 1005355A4 EP 98919780 A EP98919780 A EP 98919780A EP 98919780 A EP98919780 A EP 98919780A EP 1005355 A4 EP1005355 A4 EP 1005355A4
Authority
EP
European Patent Office
Prior art keywords
treating gastrointestinal
gastrointestinal ulcers
compositions therefor
therefor
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98919780A
Other languages
German (de)
French (fr)
Other versions
EP1005355A1 (en
Inventor
Sandor Szabo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHEMO PATHOLOGY RESOUR CENTER Inc
RADIX ORGANIZATION Inc
CHEMO PATHOLOGY RESOUR CT Inc
Original Assignee
CHEMO PATHOLOGY RESOUR CENTER Inc
CHEMO PATHOLOGY RESOUR CT Inc
RADIX ORGANIZATION Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHEMO PATHOLOGY RESOUR CENTER Inc, CHEMO PATHOLOGY RESOUR CT Inc, RADIX ORGANIZATION Inc filed Critical CHEMO PATHOLOGY RESOUR CENTER Inc
Publication of EP1005355A1 publication Critical patent/EP1005355A1/en
Publication of EP1005355A4 publication Critical patent/EP1005355A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
EP98919780A 1997-04-15 1998-04-15 Method of treating gastrointestinal ulcers and compositions therefor Withdrawn EP1005355A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4302397P 1997-04-15 1997-04-15
US43023P 1997-04-15
PCT/US1998/007686 WO1998046249A1 (en) 1997-04-15 1998-04-15 Method of treating gastrointestinal ulcers and compositions therefor

Publications (2)

Publication Number Publication Date
EP1005355A1 EP1005355A1 (en) 2000-06-07
EP1005355A4 true EP1005355A4 (en) 2002-07-17

Family

ID=21925042

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98919780A Withdrawn EP1005355A4 (en) 1997-04-15 1998-04-15 Method of treating gastrointestinal ulcers and compositions therefor

Country Status (2)

Country Link
EP (1) EP1005355A4 (en)
WO (1) WO1998046249A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1121143A2 (en) * 1998-03-27 2001-08-08 Dorothea J. Eicher Vegf and vegf-c as infant formula supplements
RU2008101791A (en) * 2005-06-17 2009-07-27 Дженентек, Инк. (Us) HEALING RAS

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0269408A2 (en) * 1986-11-26 1988-06-01 Genentech, Inc. TGF-Beta in the treatment of inflammatory disorders
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
WO1996006641A1 (en) * 1994-08-29 1996-03-07 Prizm Pharmaceuticals, Inc. Conjugates of vascular endothelial growth factor with targeted agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219998A (en) * 1990-06-04 1993-06-15 Levin Robert H Yeast-derived epidermal growth factor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0269408A2 (en) * 1986-11-26 1988-06-01 Genentech, Inc. TGF-Beta in the treatment of inflammatory disorders
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
WO1996006641A1 (en) * 1994-08-29 1996-03-07 Prizm Pharmaceuticals, Inc. Conjugates of vascular endothelial growth factor with targeted agents

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BRYAN WILLIAMS: "Vascular permeability/vascular endothelial growth factors: a potential role in the pathogenesis and treatment of vascular diseases", VASCULAR MEDICINE, vol. 1, no. 4, 1996, pages 251 - 258, XP001070847 *
FAVARD C ET AL: "PURIFICATION AND BIOLOGICAL PROPERTIES OF VASCULOTROPIN A NEW ANGIOGENIC CYTOKINE", BIOLOGY OF THE CELL, vol. 73, no. 1, 1991, pages 1 - 6, XP001070843, ISSN: 0248-4900 *
HULL M A ET AL: "ISOLATION AND CULTURE OF HUMAN GASTRIC ENDOTHELIAL CELLS", GASTROENTEROLOGY, SAUNDERS, PHILADELPHIA, PA,, US, vol. 5, no. 111, November 1996 (1996-11-01), pages 1230 - 1240, XP001068448, ISSN: 0016-5085 *
See also references of WO9846249A1 *
SZABO S ET AL: "Modulation of vascular factors by VEGF/VPF (vascular endothelial cell growth factor/vascular permeability factor) is sufficient for chronic ulcer healing and acute gastroprotection.", GASTROENTEROLOGY, vol. 112, no. 4 SUPPL., 1997, Digestive Disease Week and the 97th Annual Meeting of the American Gastroenterological Association;Washington, D.C., USA; May 11-14, 1997, pages A303, XP001068612, ISSN: 0016-5085 *

Also Published As

Publication number Publication date
WO1998046249A1 (en) 1998-10-22
EP1005355A1 (en) 2000-06-07

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Legal Events

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