DE69933771D1 - Neurotrophischer wachstumsfaktor - Google Patents

Neurotrophischer wachstumsfaktor

Info

Publication number
DE69933771D1
DE69933771D1 DE69933771T DE69933771T DE69933771D1 DE 69933771 D1 DE69933771 D1 DE 69933771D1 DE 69933771 T DE69933771 T DE 69933771T DE 69933771 T DE69933771 T DE 69933771T DE 69933771 D1 DE69933771 D1 DE 69933771D1
Authority
DE
Germany
Prior art keywords
growth factor
neurotrophic growth
bioprecursor
organism
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69933771T
Other languages
English (en)
Other versions
DE69933771T2 (de
Inventor
Hugo Alfonso Geerts
Leo Masure
Theo Frans Meert
Miroslav Cik
Donck August Ver
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27269394&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69933771(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9815283.8A external-priority patent/GB9815283D0/en
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE69933771D1 publication Critical patent/DE69933771D1/de
Application granted granted Critical
Publication of DE69933771T2 publication Critical patent/DE69933771T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69933771T 1998-07-14 1999-07-14 Neurotrophischer wachstumsfaktor Expired - Lifetime DE69933771T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB9815283 1998-07-14
GBGB9815283.8A GB9815283D0 (en) 1998-07-14 1998-07-14 Neurotrophic growth factor
US24877299A 1999-02-12 1999-02-12
US248772 1999-02-12
US32766899A 1999-06-08 1999-06-08
US327668 1999-06-08
PCT/EP1999/005031 WO2000004050A2 (en) 1998-07-14 1999-07-14 Neurotrophic growth factor

Publications (2)

Publication Number Publication Date
DE69933771D1 true DE69933771D1 (de) 2006-12-07
DE69933771T2 DE69933771T2 (de) 2007-09-13

Family

ID=27269394

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933771T Expired - Lifetime DE69933771T2 (de) 1998-07-14 1999-07-14 Neurotrophischer wachstumsfaktor

Country Status (28)

Country Link
US (1) US7544788B2 (de)
EP (2) EP1640381B1 (de)
JP (2) JP4469500B2 (de)
KR (2) KR100773776B1 (de)
CN (1) CN1243770C (de)
AT (1) ATE343594T1 (de)
AU (1) AU768472B2 (de)
BG (1) BG65518B1 (de)
BR (2) BR9912819A (de)
CA (1) CA2333910C (de)
CY (2) CY1105949T1 (de)
CZ (1) CZ303868B6 (de)
DE (1) DE69933771T2 (de)
DK (2) DK1640381T3 (de)
ES (2) ES2275349T3 (de)
HK (2) HK1045528B (de)
HR (1) HRP20010036B1 (de)
HU (1) HU226073B1 (de)
ID (1) ID27024A (de)
IL (1) IL140877A0 (de)
NO (1) NO331809B1 (de)
NZ (1) NZ509723A (de)
PL (1) PL209952B1 (de)
PT (2) PT1640381E (de)
SI (1) SI1640381T1 (de)
SK (1) SK287361B6 (de)
TR (1) TR200100074T2 (de)
WO (1) WO2000004050A2 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6593133B1 (en) 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
IL140259A0 (en) * 1998-07-06 2002-02-10 Nsgene As Neurotrophic factors
US7067473B1 (en) * 1998-07-14 2006-06-27 Janssen Pharmaceutica N.V. Neurotrophic growth factor
DK1640381T3 (da) * 1998-07-14 2014-07-14 Janssen Pharmaceutica Nv Neurotrofisk vækstfaktor
US20020002269A1 (en) 1998-09-29 2002-01-03 Jeffrey D. Milbrandt Artemin, a neurotrophic factor
EP1137774A2 (de) * 1998-12-09 2001-10-04 Amgen Inc. Grnf4, ein gdnf-ähnlicher neurotropher faktor
EP1873244A3 (de) * 1999-06-02 2008-04-02 Genentech, Inc. Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums
KR20080067719A (ko) * 2000-12-22 2008-07-21 제넨테크, 인크. Ｇｄｎｆ 리간드 족의 구성원인 아르테민의 신규 용도
US7442370B2 (en) 2001-02-01 2008-10-28 Biogen Idec Ma Inc. Polymer conjugates of mutated neublastin
US7276580B2 (en) 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
JP4499362B2 (ja) 2001-03-28 2010-07-07 バイオジェン・アイデック・エムエイ・インコーポレイテッド ニューロパシーの疼痛を処置するためのニューブラスチンポリペプチドの使用
US20040077543A1 (en) * 2001-03-28 2004-04-22 Sah Dinah W. Y. Treatment using neublastin polypeptides
US20050176746A1 (en) * 2002-05-17 2005-08-11 Frank Weber Use of compounds that are effective as selective opiate receptor modulators
JP4571776B2 (ja) * 2002-11-05 2010-10-27 Ｊｘ日鉱日石エネルギー株式会社 潤滑油組成物
ATE433759T1 (de) 2003-04-18 2009-07-15 Biogen Idec Inc Polymerkonjugiertes glycosiliertes neublastin
NZ544263A (en) 2003-06-10 2009-04-30 Nsgene As Improved secretion of neublastin
US7598059B2 (en) 2003-10-02 2009-10-06 Biogen Idec Ma Inc. Neublastin expression constructs
US8722862B2 (en) 2004-08-19 2014-05-13 Biogen Idec Ma Inc. Refolding transforming growth factor beta family proteins
BRPI0514534A (pt) * 2004-08-19 2008-06-17 Biogen Idec Inc variantes de neublastina
TWI501774B (zh) 2006-02-27 2015-10-01 Biogen Idec Inc 神經性病症之治療
US20100056440A1 (en) * 2006-03-01 2010-03-04 Biogen Idec Ma Inc. Compositions and methods for administering gdnf ligand family proteins
JP5829377B2 (ja) 2007-02-06 2015-12-09 ジュン ヨー，タイ 遺伝子治療を使用する神経変性疾患の治療および予防
NZ580947A (en) 2007-05-01 2012-05-25 Biogen Idec Inc Compositions and methods for increasing vascularization
MX2009013765A (es) * 2007-06-27 2010-02-01 Auckland Uniservices Ltd Polipeptidos y polinucleotidos para artemina y ligandos relacionados, y metodos de uso de los mismos.
US20110135648A1 (en) * 2007-08-08 2011-06-09 Biogen Idec Ma Inc. Anti-neublastin antibodies and uses thereof
JO3462B1 (ar) * 2012-08-22 2020-07-05 Regeneron Pharma أجسام مضادة بشرية تجاه gfr?3 وطرق لاستخدامها
US11225689B2 (en) * 2016-08-17 2022-01-18 The Broad Institute, Inc. Method for determination and identification of cell signatures and cell markers

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US5739307A (en) * 1995-08-28 1998-04-14 Washington University Polynucleotide encoding neurturin neurotrophic factor
US5972338A (en) * 1997-09-19 1999-10-26 Genentech, Inc. Tie ligands homologues
US6593133B1 (en) * 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
US20020055467A1 (en) * 1998-07-06 2002-05-09 Johansen Teit E. Novel neurotrophic factors
US7067473B1 (en) * 1998-07-14 2006-06-27 Janssen Pharmaceutica N.V. Neurotrophic growth factor
DK1640381T3 (da) * 1998-07-14 2014-07-14 Janssen Pharmaceutica Nv Neurotrofisk vækstfaktor
US20020002269A1 (en) * 1998-09-29 2002-01-03 Jeffrey D. Milbrandt Artemin, a neurotrophic factor
EP1137774A2 (de) † 1998-12-09 2001-10-04 Amgen Inc. Grnf4, ein gdnf-ähnlicher neurotropher faktor
JP2002051906A (ja) * 2000-08-11 2002-02-19 Nippon Platec Co Ltd Ｉｈ調理器による加熱を可能にしたアルミ箔材料及びこのアルミ箔材料を用いて成形したアルミ箔材料製食品用容器
US7276580B2 (en) * 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
WO2018191688A2 (en) † 2017-04-14 2018-10-18 Johnson Controls Techology Company Thermostat with exhaust fan control for air quality and humidity control

Also Published As

Publication number Publication date
PL209952B1 (pl) 2011-11-30
CY1115496T1 (el) 2017-01-04
SI1640381T1 (sl) 2014-07-31
PT1640381E (pt) 2014-07-17
JP4469500B2 (ja) 2010-05-26
BG65518B1 (bg) 2008-10-31
BR9912819A (pt) 2001-05-02
EP1097167B1 (de) 2006-10-25
SK142001A3 (en) 2002-02-05
WO2000004050A2 (en) 2000-01-27
ID27024A (id) 2001-02-22
CZ200128A3 (cs) 2001-08-15
BRPI9912819B1 (pt) 2018-09-18
PL348431A1 (en) 2002-05-20
CY1105949T1 (el) 2011-04-06
WO2000004050A3 (en) 2000-11-09
IL140877A0 (en) 2002-02-10
JP4624476B2 (ja) 2011-02-02
HK1092477A1 (en) 2007-02-09
KR100712223B1 (ko) 2007-04-27
CN1342165A (zh) 2002-03-27
EP1097167A2 (de) 2001-05-09
CA2333910A1 (en) 2000-01-27
NZ509723A (en) 2004-01-30
US7544788B2 (en) 2009-06-09
CZ303868B6 (cs) 2013-06-05
NO20010212D0 (no) 2001-01-12
ES2479067T3 (es) 2014-07-23
AU768472B2 (en) 2003-12-11
JP2002520042A (ja) 2002-07-09
BRPI9912819B8 (pt) 2021-05-25
US20050233359A1 (en) 2005-10-20
HU226073B1 (en) 2008-04-28
JP2010158241A (ja) 2010-07-22
SK287361B6 (sk) 2010-08-09
BG105107A (en) 2001-10-31
KR100773776B1 (ko) 2007-11-12
EP1640381B1 (de) 2014-05-14
EP1640381A3 (de) 2007-01-31
KR20010083108A (ko) 2001-08-31
NO331809B1 (no) 2012-04-10
DK1640381T3 (da) 2014-07-14
PT1097167E (pt) 2007-02-28
HK1045528A1 (en) 2002-11-29
ES2275349T3 (es) 2007-06-01
CN1243770C (zh) 2006-03-01
CA2333910C (en) 2016-11-15
HUP0102821A3 (en) 2003-09-29
HRP20010036B1 (en) 2010-06-30
TR200100074T2 (tr) 2001-11-21
HUP0102821A2 (hu) 2001-11-28
NO20010212L (no) 2001-03-14
DK1097167T3 (da) 2007-03-12
HRP20010036A2 (en) 2001-12-31
ATE343594T1 (de) 2006-11-15
HK1045528B (zh) 2006-10-27
DE69933771T2 (de) 2007-09-13
EP1640381A2 (de) 2006-03-29
KR20060061408A (ko) 2006-06-07
EP1097167B2 (de) 2018-12-12
AU5283299A (en) 2000-02-07

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