CA2270195A1 - Pharmaceutical composition for treatment of diabetes - Google Patents
Pharmaceutical composition for treatment of diabetesInfo
- Publication number
- CA2270195A1 CA2270195A1 CA002270195A CA2270195A CA2270195A1 CA 2270195 A1 CA2270195 A1 CA 2270195A1 CA 002270195 A CA002270195 A CA 002270195A CA 2270195 A CA2270195 A CA 2270195A CA 2270195 A1 CA2270195 A1 CA 2270195A1
- Authority
- CA
- Canada
- Prior art keywords
- radix
- rhizoma
- diabetes
- treatment
- cortex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 4
- 229940079593 drug Drugs 0.000 abstract 4
- 239000008280 blood Substances 0.000 abstract 3
- 210000004369 blood Anatomy 0.000 abstract 3
- 230000003247 decreasing effect Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 2
- 241000748223 Alisma Species 0.000 abstract 1
- 241000208340 Araliaceae Species 0.000 abstract 1
- 206010004542 Bezoar Diseases 0.000 abstract 1
- 241000190633 Cordyceps Species 0.000 abstract 1
- 241000628997 Flos Species 0.000 abstract 1
- 241001251094 Formica Species 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 241000237903 Hirudo Species 0.000 abstract 1
- 241000180649 Panax notoginseng Species 0.000 abstract 1
- 235000003143 Panax notoginseng Nutrition 0.000 abstract 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 abstract 1
- 235000003140 Panax quinquefolius Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000008434 ginseng Nutrition 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 abstract 1
- 239000008820 moutan cortex Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Abstract
The present invention relates to a pharmaceutical composition containing a combination of natural drugs for treatment of diabetes.
More specifically, the present invention relates to a composition containing 17 kinds of main natural drugs, i.e. Cordyceps, Bezoar bovis, Carthami flos, Astragali radix, Hirudo, Polygoni cuspidati radix, Polygonati falcati rhizoma, Euonymi lignum suberalatum, Corni fructus, Moutan cortex, Lycii cortex radicis, Lycii fructus, Atractylodis rhizoma alba, Atractylodis rhizoma, Coptidis rhizoma, Puerariae radix and Rehmaniae radix crudae. In addition to 17 kinds of main natural drugs, if desired, the composition of the present invention can contain one or more supplementary natural drugs selected from the group consisting of Liriopsis tuber, Cistanchis herba, Adenophorae radix, Salviae radix, Ginseng radix rubra, Anemarrhenae rhizoma, Pachymae fungus, Phellodendri cortex, Mori radicis cortex, Schizandrae fructus, Galli stomachichum corium, Trichosanthis radix, Rhei rhizoma, Dioscoreae rhizoma, Alisma rhizoma, Polygoni multiflori radix, Galls rhois, Formica fuses L., Sanchi ginseng, Margaritum and Gecko. The composition of the present invention is an agent for prevention of diabetes and for prevention and treatment of complications concomitant with diabetes by decreasing the blood sugar level of diabetic patients, but not decreasing the blood sugar level of normal person, and decreasing the blood lipid level, and therefore, is particularly effective for treatment of noninsulin-dependent diabetes (Type II diabetes) as well as insulin-dependent diabetes (Type I diabetes).
More specifically, the present invention relates to a composition containing 17 kinds of main natural drugs, i.e. Cordyceps, Bezoar bovis, Carthami flos, Astragali radix, Hirudo, Polygoni cuspidati radix, Polygonati falcati rhizoma, Euonymi lignum suberalatum, Corni fructus, Moutan cortex, Lycii cortex radicis, Lycii fructus, Atractylodis rhizoma alba, Atractylodis rhizoma, Coptidis rhizoma, Puerariae radix and Rehmaniae radix crudae. In addition to 17 kinds of main natural drugs, if desired, the composition of the present invention can contain one or more supplementary natural drugs selected from the group consisting of Liriopsis tuber, Cistanchis herba, Adenophorae radix, Salviae radix, Ginseng radix rubra, Anemarrhenae rhizoma, Pachymae fungus, Phellodendri cortex, Mori radicis cortex, Schizandrae fructus, Galli stomachichum corium, Trichosanthis radix, Rhei rhizoma, Dioscoreae rhizoma, Alisma rhizoma, Polygoni multiflori radix, Galls rhois, Formica fuses L., Sanchi ginseng, Margaritum and Gecko. The composition of the present invention is an agent for prevention of diabetes and for prevention and treatment of complications concomitant with diabetes by decreasing the blood sugar level of diabetic patients, but not decreasing the blood sugar level of normal person, and decreasing the blood lipid level, and therefore, is particularly effective for treatment of noninsulin-dependent diabetes (Type II diabetes) as well as insulin-dependent diabetes (Type I diabetes).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019960051572A KR100195886B1 (en) | 1996-11-01 | 1996-11-01 | Pharmaceutical composition for treating diabetes mellitus |
KR1996/51572 | 1996-11-01 | ||
PCT/KR1997/000197 WO1998019688A1 (en) | 1996-11-01 | 1997-10-21 | Pharmaceutical composition for treatment of diabetes |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2270195A1 true CA2270195A1 (en) | 1998-05-14 |
CA2270195C CA2270195C (en) | 2002-07-23 |
Family
ID=19480579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002270195A Expired - Fee Related CA2270195C (en) | 1996-11-01 | 1997-10-21 | Pharmaceutical composition for treatment of diabetes |
Country Status (12)
Country | Link |
---|---|
US (1) | US5916555A (en) |
EP (1) | EP0941103B1 (en) |
JP (1) | JP2001506589A (en) |
KR (1) | KR100195886B1 (en) |
CN (1) | CN1079027C (en) |
AU (1) | AU713883B2 (en) |
CA (1) | CA2270195C (en) |
DE (1) | DE69710095T2 (en) |
DK (1) | DK0941103T3 (en) |
ES (1) | ES2171903T3 (en) |
HK (1) | HK1022835A1 (en) |
WO (1) | WO1998019688A1 (en) |
Families Citing this family (93)
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KR19990009027A (en) * | 1997-07-07 | 1999-02-05 | 최수부 | Health foods containing herbal medicines |
US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
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US7326404B2 (en) * | 2000-05-31 | 2008-02-05 | Vuksan Holdings Inc. | Konjac-mannan and ginseng compositions and methods and uses thereof |
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US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
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KR20030020714A (en) * | 2001-09-04 | 2003-03-10 | (주)바이오뉴트리젠 | Composition for lowering blood lipid level comprising a lycium root extract |
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KR100473529B1 (en) * | 2002-01-04 | 2005-03-09 | 씨제이 주식회사 | Composition comprising an extract of sungisan crude drug complex as an effective ingredient for preventing and treating diabetes |
KR20030078565A (en) * | 2002-03-30 | 2003-10-08 | 백일성 | Phamaceutical composition comprising GLYCYRRHIZAE RADIX, PERILLAE SEMEN, PEUCEDANI RADIX, SCHIZANDRAE FRUCTUS, ASPARAGI RADIX, MORI CORTEX RADICIS and PERILLAE FOLIUM as main ingredients |
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US7772195B2 (en) * | 2004-07-29 | 2010-08-10 | Board Of Trustees Of Michigan State University | Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia |
ES2349043T3 (en) * | 2004-08-19 | 2010-12-22 | Biogen Idec Ma Inc. | NEUBLASTIN VARIANTS. |
DE602005022457D1 (en) * | 2004-08-19 | 2010-09-02 | Biogen Idec Inc | Neublastin VARIATIONS |
CA2592733C (en) * | 2005-01-31 | 2011-05-17 | Dong Wha Pharm. Ind. Co., Ltd. | Pharmaceutical composition for treating nephropathy and healthy food comprising herb extracts |
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KR101498665B1 (en) * | 2013-01-10 | 2015-03-05 | 한국 한의학 연구원 | Pharmaceutical composition and functional food for prevention or treatment of diabetic complications or angioedema comprising natural extract |
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US20140358094A1 (en) * | 2013-05-29 | 2014-12-04 | Nano And Advanced Materials Institute Limited | Composition, the nano-emulsion and transdermal patch, methods of preparation and use thereof for treating traumatic injuries |
CN104435909A (en) * | 2013-09-25 | 2015-03-25 | 阿不力克木·阿布都热依木 | Uyghur herbal medicine for treating diabetes mellitus |
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CN107692187A (en) * | 2017-08-22 | 2018-02-16 | 华加云海健康科技(青岛)有限公司 | One kind improves liver function and reduces postprandial blood sugar ramp-up rate, and gradually reduces the food of postprandial blood sugar |
CN107456526A (en) * | 2017-08-25 | 2017-12-12 | 郭玉岩 | A kind of Chinese medicine composition treated after diabetes ACS stentings |
CN108402221A (en) * | 2018-05-06 | 2018-08-17 | 滦南愿心堂商贸有限公司 | Natural plants blood glucose decomposes tea |
CN109170099A (en) * | 2018-10-22 | 2019-01-11 | 宋子刚 | Has the eight-treasure cake and preparation method thereof for reducing blood glucose effect |
KR102133015B1 (en) * | 2018-10-26 | 2020-07-10 | 양성심 | Health functional food composition for prevention of diabetes |
US20200237846A1 (en) * | 2019-01-29 | 2020-07-30 | Hongping Tan | Cortex lycii tea formula |
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1996
- 1996-11-01 KR KR1019960051572A patent/KR100195886B1/en not_active IP Right Cessation
-
1997
- 1997-10-21 ES ES97910622T patent/ES2171903T3/en not_active Expired - Lifetime
- 1997-10-21 JP JP52123498A patent/JP2001506589A/en not_active Ceased
- 1997-10-21 DK DK97910622T patent/DK0941103T3/en active
- 1997-10-21 WO PCT/KR1997/000197 patent/WO1998019688A1/en active IP Right Grant
- 1997-10-21 DE DE69710095T patent/DE69710095T2/en not_active Expired - Fee Related
- 1997-10-21 AU AU47938/97A patent/AU713883B2/en not_active Ceased
- 1997-10-21 CN CN97199360A patent/CN1079027C/en not_active Expired - Fee Related
- 1997-10-21 CA CA002270195A patent/CA2270195C/en not_active Expired - Fee Related
- 1997-10-21 EP EP97910622A patent/EP0941103B1/en not_active Expired - Lifetime
- 1997-10-30 US US08/961,069 patent/US5916555A/en not_active Expired - Fee Related
-
2000
- 2000-03-23 HK HK00101815A patent/HK1022835A1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69710095D1 (en) | 2002-03-14 |
ES2171903T3 (en) | 2002-09-16 |
WO1998019688A1 (en) | 1998-05-14 |
CA2270195C (en) | 2002-07-23 |
AU4793897A (en) | 1998-05-29 |
CN1235551A (en) | 1999-11-17 |
KR100195886B1 (en) | 1999-06-15 |
CN1079027C (en) | 2002-02-13 |
DK0941103T3 (en) | 2002-04-15 |
EP0941103A1 (en) | 1999-09-15 |
JP2001506589A (en) | 2001-05-22 |
EP0941103B1 (en) | 2002-01-23 |
KR19980033798A (en) | 1998-08-05 |
AU713883B2 (en) | 1999-12-16 |
DE69710095T2 (en) | 2002-08-22 |
US5916555A (en) | 1999-06-29 |
HK1022835A1 (en) | 2000-08-25 |
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