CA2054706A1 - Very large scale immobilized polymer synthesis - Google Patents

Very large scale immobilized polymer synthesis

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Publication number
CA2054706A1
CA2054706A1 CA002054706A CA2054706A CA2054706A1 CA 2054706 A1 CA2054706 A1 CA 2054706A1 CA 002054706 A CA002054706 A CA 002054706A CA 2054706 A CA2054706 A CA 2054706A CA 2054706 A1 CA2054706 A1 CA 2054706A1
Authority
CA
Canada
Prior art keywords
substrate
large scale
polymer synthesis
immobilized polymer
scale immobilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002054706A
Other languages
French (fr)
Other versions
CA2054706C (en
Inventor
Michael C. Pirrung
J. Leighton Read
Stephen P. A. Fodor
Lubert Stryer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymetrix Inc
Original Assignee
Michael C. Pirrung
J. Leighton Read
Stephen P. A. Fodor
Lubert Stryer
Affymax N.V.
Affymax Technologies N.V.
Affymetrix, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27001838&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2054706(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Michael C. Pirrung, J. Leighton Read, Stephen P. A. Fodor, Lubert Stryer, Affymax N.V., Affymax Technologies N.V., Affymetrix, Inc. filed Critical Michael C. Pirrung
Priority to CA 2278883 priority Critical patent/CA2278883C/en
Priority to CA 2278878 priority patent/CA2278878C/en
Publication of CA2054706A1 publication Critical patent/CA2054706A1/en
Application granted granted Critical
Publication of CA2054706C publication Critical patent/CA2054706C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C08G69/00Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/809Multifield plates or multicontainer arrays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • Y10T428/31971Of carbohydrate
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer

Abstract

A method and device for preparing desired sequences on a substrate at known locations. Known locations (10) of a substrate (2) are irradiated by way of a mask (8) so as to activate a material (4) for binding. The substrate is then exposed to a first material (12) for binding thereto. Second locations (14) are then irradiated through a mask and exposed to a second material (16). A variety of sequences may be formed through selective irradiation of the substrate followed by application of selected materials. A reactor system and fluorescence detection system are also dis-closed.
CA 2054706 1989-06-07 1990-06-07 Very large scale immobilized polymer synthesis Expired - Lifetime CA2054706C (en)

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CA 2278883 CA2278883C (en) 1989-06-07 1990-06-07 Very large scale immobilized peptide synthesis
CA 2278878 CA2278878C (en) 1989-06-07 1990-06-07 Very large scale immobilized peptide synthesis

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US36290189A 1989-06-07 1989-06-07
US362,901 1989-06-07
US492,462 1990-03-07
US07/492,462 US5143854A (en) 1989-06-07 1990-03-07 Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
PCT/NL1990/000081 WO1990015070A1 (en) 1989-06-07 1990-06-07 Very large scale immobilized peptide synthesis

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CA 2278883 Expired - Lifetime CA2278883C (en) 1989-06-07 1990-06-07 Very large scale immobilized peptide synthesis
CA 2278878 Expired - Lifetime CA2278878C (en) 1989-06-07 1990-06-07 Very large scale immobilized peptide synthesis
CA 2054706 Expired - Lifetime CA2054706C (en) 1989-06-07 1990-06-07 Very large scale immobilized polymer synthesis
CA 2391491 Abandoned CA2391491A1 (en) 1989-06-07 1990-06-07 Very large scale immobilized peptide synthesis

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